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Science 314 , 467471 (2006)

Figure 3 3.1 Nanoparticles enhance NK cells homing A variety of nanoparticles have been shown to promote NK cells homing, such as iron oxide nanoparticles bound to the surface of primary NK cells can not only significantly enhance NK cells homing to tumors but also show significant anti-tumor efficacy by increasing the expression of granzyme and perforin in tumor cells compared to unmodified NK cells (73)