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2 Otoprotection in Zebrafish Lateral Line Hair Cells Uribe et al., Frontiers in Cellular Neuroscience (2015) This paper from the Coffin laboratory (with WSU co-authors) tested whether Dihexa could protect zebrafish lateral line hair cells (homologous to mammalian inner ear hair cells) from aminoglycoside-induced ototoxicity

It is important to note that in these studies, specific isoforms are often not reported, or they are reported to include classic PRKCA and PRKCE, possibly due to their availability in non-neuronal cell lines (platelets) (Wang et al., 1999)

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Because the needle stays in the fatty layer, there is less chance of catching a nerve or a blood vessel than with a deeper injection, which is one reason some clinicians prefer it for maintenance dosing

To view a copy of this license, visit About this article Cite this article Draper, C.F., Duisters, K., Weger, B