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While a marked increase in tumor volume was observed in the control group by day 15, no significant tumor enlargement was detected in the group treated with Spirulina polysaccharides ( In the hepatocellular carcinoma (HCC) model, Spirulina has been observed to increase survival and significantly reduce AFP levels, a tumor marker, as well as the number and volume of hepatic nodules
It also helps maintain the activity of other key antioxidants like vitamins C and E, making it essential for cellular health and resilience
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It is evident that HMOX1 may play an important role in mediating embryonic ferroptosis, and its overexpression promotes oxidation and induces ferroptosis through increased iron accumulation and lipid peroxidation [32]
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