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Two pathways differentially linking tau depositions, oxidative stress, and neuronal loss to apathetic phenotypes in progressive supranuclear palsy

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Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation

For instance, Elevated levels of MDA in Tunisian patients, as observed in biopsies from individuals with CD, suggest the involvement of oxidative stress in the pathophysiology of IBD (176)