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Ferguson G, Bridge W

Reduced mRNA expression of Cyp7a1 in Insr P1195L/ +/HFD mice on re-feeding was significantly increased by fat transplantation, suggesting that modulation of metabolism in adipocytes by WAT transplantation may elicit alteration in BA physiology in liver

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SURPASS-CN-MONO is a randomized, double-blind, placebo-controlled phase III study designed to evaluate the efficacy and safety of tirzepatide monotherapy compared to placebo in people with type 2 diabetes