We also care for many individuals with digestive disorders like Crohns disease or celiac disease, which can make it challenging to get enough B12 from diet alone
Genome Res
A comprehensive safety and tolerability study evaluated approximately 900 participants across six trials with the following protocols: Subcutaneous/Intravenous Protocols: Single doses ranging from 25 to 400 mcg/kg body weight were tested
24 25 Some patients may experience recurrence or worsening of symptoms when the interval between injections is extended or extended too quickly, and report that continuation of frequent intramuscular hydroxocobalamin injections, varying between twice weekly and once every three to four weeks, 65 is needed to remain asymptomatic
Your Overall Health Underlying health conditions, such as gastrointestinal disorders (like Crohns disease, celiac disease, or atrophic gastritis) that impair nutrient absorption, or certain medications you may be taking, can influence how your body absorbs and utilizes B12