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Briefly, under visualization with an operating microscope, 50 L of the formulation was injected using a 25 G (Gauge) 1 inch needle through the tympanic membrane into the superior posterior quadrant

Non-immunogenic , meaning they are unlikely to trigger allergic or inflammatory reactions

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Doessing, S., et al

Class-based models put exposure per milligram about 10% to 25% above the 240 lb trial mean across this range. Resting heart-rate response may also exceed the trials near-zero average