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Overall, the uniquely rapid need for neutrophil effector functions, such as NETosis, phagocytosis and degranulation, to be mobilized quickly in the innate immune response necessitates brisk production of NADPH, which is chiefly controlled by the PPP rate-limiting activity of G6PD

[DOI] [PubMed] [Google Scholar] Mudgil P

For intranasal administration, commonly reported empirical dosing includes 100-200 mcg per nostril taken once or twice daily (obviously, BPC-157 should first be reconstituted in bacteriostatic water at an appropriate concentration for nasal delivery)

Treatment time varies from 15 minutes for small areas to 60 minutes for large zones

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