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In fact, Hans probe could be potentially used as a peroxynitrite probe, similar to the H 2 O 2 probe Hyper, which is reversibly oxidized by H 2 O 2 and reduced by thioredoxin 35

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gingivalis LPS is involved in inducing the production of proinflammatory cytokines such as TNF- and IL-6 in glomerular endothelial cells by binding to TLR2 and TLR4, as well as the production of anti - inflammatory cytokines such as TGF- to promote glomerular sclerosis (Sawa et al., 2014)

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