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Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner

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Inside the cells, the benzoquinone head of CoQ 10 exists in three interchangeable oxidation states, i.e., the fully reduced ubiquinol (CoQ 10 H 2 ), the ubisemiquinone intermediate (CoQ 10 H), and the fully oxidized ubiquinone (CoQ 10 )

This is due to the role that glutathione plays in squelching free radicals

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