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Since redox processes in the cell are highly regulated, the presence of glutathione in the periplasm at such high levels strongly indicates that this molecule also plays a role in the redox homeostasis of the periplasm, similar to its role in the ER (Birk et al., 2013

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Emerging evidence increasingly suggests that cellular senescence, iron overload, and fibrosis collectively form a critical pathological axis that significantly contributes to the persistence and severity of the disease

So fhren Phenobarbital, Phenytoin und Carbamazepin ber das hepatische P450-Enzymsystem zu einem erhhten Katabolismus der Schilddrsenhormone