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Sirtuin-1 activation controls tumor growth by impeding Th17 differentiation via STAT3 deacetylation

Human clinical evidence is promising but remains limited in several areas

However, metabolic malleability in invasive tumors results in recurrence as well as drug-resistant clones with more complex metabolic profiles

To make regular consumption of watermelon products (juice, extract, powder, and puree) more feasible, food technologies like spray drying and freeze-drying should be used to concentrate bioactive chemicals into smaller volumes

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