At a molecular level, glutathione is a tripeptide containing three amino acids: glycine, cysteine, and glutamic acid, and each of them offers a set of important health benefits in humans
Desired drug payloads can thus be entrapped, through diverse chemical reactions (i.e., covalent binding), by steric hindrance (i.e., non-covalent binding), bonded on the surface or physically dispersed/adsorbed within their meshes in a versatile manner (Kim et al., 2009
doi: 10.1016/j.bcp.2009.07.023
Inhibiting system Xc reduces GSH production, thereby diminishing the activity of GPX4 and leading to ROS accumulation, ultimately driving ferroptosis in CRC cells [61, 69-72]
Roughly 40% of individuals with type 2 diabetes and one-third with type 1 diabetes will develop CKD