FASEB J (2003) 17:1195214
doi: 10.1080/09687860500244262
Srivastava R, Aslam M, Kalluri SR, Schirmer L, Buck D, Tackenberg B, Rothhammer V, Chan A, Gold R, Berthele A, Bennett JL, Korn T, Hemmer B
While eye patches have become a staple in beauty routines around the world, Korean brands have long been using them as everyday rituals rather than once-in-a-while pampering sessions
However, studies only points to the key role of BH4 in protecting cells when GPX4 is inhibited, and its influence on lipid peroxidation is unrelated to its cofactors, but the specific mechanism remains unclear ( SLC7A11 (xCT) With the deepening of ferroptosis research, studies have strengthened the strategy of using the Cystine/Glutamate reverse transporter SLC7A11 (xCT) pathway to regulate ferroptosis, the principle of which is also based on the antioxidant axis system x c - -GSH-GPX4, but the focus falls on the key precursor system of the system x c - ( c - is actually a sodium-independent antiporter, consisting of the heavy chain subunit solute carrier family 3 member 2 (SLC3A2) and the light chain subunit SLC7A11 ( c - ( Figure 1B )
