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Antioxidants 8(5):126

TAR DNA binding protein 43 (TDP-43) is a marker that has been identified as both a pathological and biochemical indicator in ALS (172)

Review: soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation

The main cerebral target for THC is type-1 cannabinoid receptors (CB1R), which are widely expressed in the brain and regulate various functions including neurotransmitter release, neuro-astroglial communication, and cellular bioenergetic processes [29,30,31,32]

The reviewed data support the concept that OS is involved in multiple risk factors-associated LUTS, although further studies are needed to confirm the causative relationship