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The peptide demonstrates dual-phase mechanisms: acute phase preservation of ischemic tissue through anti-apoptotic signaling via Akt activation, and chronic phase activation of cardiac progenitor cells (c-kit+ populations) that contribute to myocardial repair through both structural replacement and paracrine support, with studies showing 200% increases in progenitor cell mobilization and cardiac homing

Because it mimics a natural compound produced by the body, the risk of side effects is minimal

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HY, JY, JD, YS, ST, TR, D-LW, JL, SP, and NC performed and analyzed the experiments

Some researchers have developed azoles by combining 7-(diethyl)-aminocoumarin to the pharmacophore of fluconazole to improve the efficiency of location