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Kluczowym parametrem jest tutaj odpowiednie pH peptyd miedziowy zachowuje stabilno w zakresie pH zblionym do neutralnego (ok

The copper ion is chelated primarily through the imidazole nitrogen of histidine and the alpha-amino nitrogen of glycine, creating a stable, biologically active complex

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This protocol consists of infusing half the 36 mM NAC dose over a 1-hour period starting at 2 hours after the APAP dose, followed by 1/6 of the dose over the next 4-hour period and then 1/3 of the dose over an additional 16 hours