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Since Provenge (sipuleucel-T) was approved by the FDA as the first cancer vaccine for prostate cancer, peptide vaccine therapy has been widely used for other cancers, including gastric, colorectal, and pancreatic [162]

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[13] NAD+ plays a central role in cellular energy metabolism and is required for the proper function of mitochondria

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For In vitro study: 2 g of formulation was taken for in vitro diffusion study using Franz diffusion cell in phosphate buffer pH 7.4 at 37C across dialysis membrane with l2-l4kd molecular weight cut off, under continuous stirring