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Further, it may stimulate angiogenesis by interacting with cell surface ATP synthase enzymes [23, 26]

[3] [4] Clinical trials have demonstrated substantial reductions in hemoglobin A1c (up to 2.5% reduction from baseline) and body weight (up to 20% reduction from baseline) in the SURPASS and SURMOUNT clinical trial programs

Researchers achieve the best results when the compound supplements rather than substitutes for appropriate diet and exercise

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However, at the time, some clinicians and compounding pharmacies argued the agency overstepped