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However, EMS lesions inherently exhibit impaired mitophagy, leading to the persistent accumulation of dysfunctional mitochondria and increased ROS production

The effect is promising, but again, it came from a very small sample, so read it as "deserves more research" rather than "proven for everyone." Several small clinical trials on oral glutathione, some using doses similar to this product, have shown modest reductions in melanin index and improvements in skin brightness over 4 to 12 weeks

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J Assist Reprod Genet 35(11):20312035

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