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Lipoic acid was found to upregulate the expression of -GCL and other antioxidant enzymes via the activation of the nuclear factor E2-related factor 2 (Nrf2)-dependent pathway (31, 33)

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The supplement CDG is viewed as a potential clinical application for the regulation of estrogen metabolism and as a lipid-lowering agent (it helps maintain normal cholesterol levels)

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Additionally, counteracted/attenuated were severe muscle disturbances in rats with abdominal aorta occlusion [82], tumor cachexia (severe muscle wasting) [11], and different electrolyte disturbances [54,83,84,85]