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The signals initiated by the retinoids begin after the early phase of embryonic development (gastrulation) where retinoic acid is very important for organ development, including the heart, eyes, ears, lungs, limbs, visceral organs

Clinically, HT presents with local symptoms due to neck compression and systemic symptoms due to hypothyroidism (Caturegli et al

Most people dont even know they are dehydrated or vitamin deficient, and those who do are quite often taking supplements that dont actually give them what they need

S Afr Med J