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doi:10.1016/j.amjcard.2007.02.065 87

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We found an accumulation of proline, glutamate, 2-oxoglutarate, malate, and a lower NAD + to NADH ratio inside the gdh3 / gdh3 mutant relative to wild-type cells when grown in proline medium

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It is naturally produced in the liver and plays a critical role in various bodily processes, including tissue building and repair, immune system functioning, and the detoxification of chemicals and pollutants

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