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A recent proposal suggests employing senolytics as a secondary adjuvant therapy in cancer treatment following a one-two-punch approach 626
Goncalves-Ribeiro S, Diaz-Maroto NG, Berdiel-Acer M, Soriano A, Guardiola J, Martinez-Villacampa M et al
Notably, KDs enhance conventional treatments, showing synergy with metformin (68% tumor suppression), chemotherapy (70% remission in resistant models), and immunotherapy (delayed progression in resistant cancers)
[DOI] [PMC free article] [PubMed] [Google Scholar] 870.Manferdini C., Paolella F., Gabusi E., Gambari L., Piacentini A., Filardo G., Fleury-Cappellesso S., Barbero A., Murphy M., Lisignoli G