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Prescription pathway: Once your GP has established the need for ongoing B12 therapy, they can issue a repeat prescription for home use

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Weight-Based Dosing Guidelines Under 160 lbs : 300 mcg daily 160-200 lbs : 400 mcg daily (standard protocol) 200-250 lbs : 500 mcg daily Over 250 lbs : 500 mcg daily (may require extended cycling) Heavier individuals often require higher doses due to increased adipose tissue mass and potentially altered peptide distribution

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These findings thus point to a close connection between the deregulated DNA methylation of imprinted loci with the risk of ASD at birth and has motivated attempts to uncover critically imprinted domains of predictive value for ASD prognosis

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