This protective effect is mediated through the solute carrier family 38 member 9 (SLC38A9)-mechanistic target of rapamycin kinase (MTOR) axis, which coordinates cholesterol sensing and signaling with the upregulation of solute carrier family 7 member 11 (SLC7A11) and glutathione peroxidase 4 (GPX4), key ferroptosis suppressors [60]
Focal bile duct proliferation with cystic dilation of ducts may occur
Talarmin H, Rescan C, Cariou S, Glaise D, Zanninelli G, Bilodeau M, Loyer P et al
Ferroptosis does not possess autophagic characteristics, for example, the accumulation of autophagic vacuoles (enclosed double-layer membrane structures)
plantarum and Pediococcus acidilactici for 30-days, showed total remission of 53.1% in the probiotic-treated compared to 28.1% in the placebo groups, respectively