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TRPM2 channel in transfected cell lines is gated by extracellular and intracellular ROS, possibly by interacting with the ADP ribose pyrophosphatase enzyme in the tail of the protein C domain (Perraud et al., 2001

Pain or discomfort around the anal area, particularly when sitting or during bowel movements

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Investigation of in vitro and in vivo metabolism of Schisandrin B from Schisandrae Fructus by liquid chromatography coupled electrospray ionization tandem mass spectrometry