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It is necessary to follow this timeline when the product is used at home or at the hospital

Megaloblastic anemia Diminished activity of methionine synthase in vitamin B 12 deficiency inhibits the regeneration of tetrahydrofolate (THF) and traps folate in a form that is not usable by the body ( Figure 3 ), resulting in symptoms of folate deficiency even in the presence of adequate folate

See LABORATORY TESTS for monitoring B12 levels and adjustment of dosage

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