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In contrast, DFP treatment significantly decreased Fe 2+ levels in optic nerve tissue, downregulated TFR1 and Iba-1 expression, and inhibited iron deposition, ferroptosis, microglial activation, and astrocyte proliferation, thereby reducing myelin loss and optic nerve damage in MS mice (Rayatpour et al., 2022)

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Treatment and control strategies for gut disorders, including EE, primarily focus on improving gut health, reducing inflammation, and addressing the underlying causes, such as poor WASH conditions and repeated enteric infections

Under stress conditions, GABA supplementation enhances GABA shunt activity, augments endogenous GABA levels, and boosts the efficiency of photosynthesis and antioxidative enzymes