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Common methods include radiolabeling (attaching a detectable isotope to the compound and tracking its distribution via imaging), microdialysis (sampling interstitial fluid directly from brain tissue), and post-mortem tissue analysis measuring compound concentrations in specific brain regions

Geroscience-guided repurposing of FDA-approved drugs to target aging: a proposed process and prioritization

[4] When this happens, the body receives a signal from the brain indicating that it is already full, making you less likely to eat

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