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The most clinically relevant efficacy data came from METAOD005, a 12-week randomized double-blind placebo-controlled study

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PHGDH is the rate-limiting enzyme for de novo serine synthesis, catalyzing the conversion of D-3-phosphoglycerate to 3-phosphohydroxypyruvate, the first critical step in serine biosynthesis [90,91]

Discard sooner if: The solution becomes cloudy Contamination is suspected Lab SOPs specify a shorter timeframe Factors That Affect Stability Storage Conditions Direct sunlight, extreme heat, or freezing reduce shelf life