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Ito K, Hanazawa T, Tomita K, Barnes PJ, Adcock IM: Oxidative stress reduces histone deacetylase-2 activity and enhances IL-8 gene expression: role of tyrosine nitration

This result has been independently confirmed in a larger cross-sectional study (Sim 2010)

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Therefore, immune system strategies to fight against the infection would accidentally destroy ACTH, consequently causing an alteration in the cortisol dynamics in COVID-19 patients (Pal 2020)

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