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1999 Jan 15;48(2):203-9

Studies have suggested that the sleep-wake cycle is profoundly affected with age marked by insomnia, sleep fragmentation, and daytime sleepiness that trigger the neurodegeneration and significantly affects the mental health and longevity in elderly subjects (Parhizkar and Holtzman, 2025)

We demonstrated that the BPC 157 treatment protocol was also efficacious when it was applied on day 3, immediately after the constricting ring was removed (Table 3, Figures 18 and 20-22), as shown by its subsequent rapid effect on the appearance of the arcade vessels

MAO-B, monoamine oxidase B.) Genetic susceptibility also plays a role

[DOI] [PubMed] [Google Scholar] 526.Keane L., Clarke G., Cryan J.F