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The CISD1 protein and CISD2 protein, which are present in mitochondria and the endoplasmic reticulum (ER), inhibit ferroptosis by reducing iron uptake from mitochondria and ROS production, respectively [57, 58]

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(PubMed) Mei Z, Cogswell ME, Looker AC, et al

This exposure results in the creation of aqueous pores within the lamellar lipid regions of the SC, thereby facilitating the drug diffusion across the skin barrier [192, 244]

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