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10.1007/s11357-023-00728-2 47 GhoneumA.AbdulfattahA

Toxins 12 (3), 195

On the other hand, despite sCT-induced neuronal activation in the AP of RAMP 1/3 KO HFD-fed mice, it did not result in an anorectic effect on day 1 of treatment suggesting the necessity of AMY 1 R and AMY 3 R to induce anorexia and that this circuitry is independent of signalling at the core CTR receptor

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Early research into the structure-function relationships of the GH molecule identified the C-terminal region, specifically residues 176191 as a domain with particular relevance to metabolic activity in laboratory models