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Most clinical trials have shown it is well accepted by most patients and the side effects have mostly been negligible and very few have occurred

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Pregnancy and lactation represent relative contraindications given absence of human safety data in these populations despite reassuring preclinical reproductive toxicology studies

Unlike fat-soluble vitamins that require fat for absorption and are stored in the liver, water-soluble vitamins like B12 are processed more quickly by the body and are not stored for long-term use

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