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ATRA failed to exert an effect on the GS promoter and had no effect on Nrf2 or NFB expression

Generally, it should be kept at room temperature, away from light, heat, and moisture

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Individuals with a personal history of acnewhether during adolescence or adulthoodmay theoretically be more susceptible, as their skin may already have a propensity towards follicular inflammation and altered sebaceous gland activity