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Lipocalin-2 mediates non-alcoholic steatohepatitis by promoting neutrophil-macrophage crosstalk via the induction of CXCR2

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This metabolic regulatory function may synergize with caloric restriction, which is a strategy proven to impede the development of lupus-like disease in New Zealand Black (NZB) and NZBNew Zealand White (NZW) F1 mice (161, 162)

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