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"If you were a betting person, you would bet against an animal study being relevant to humans in the clinical context," Caulfield said

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It is also well-established that cellular ATP is involved in the synthesis of reactive oxygen species (ROS) which scavenge antioxidants and that it is an energy source for antioxidant synthesis 11

Johns Wort may affect how doxycycline is metabolized, potentially lowering its effectiveness