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Our findings indicate that all three administration routes effectively increase serum B12 levels, with no statistically significant differences among them

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The upregulation and activation of 7nAChR subsequently activate several signaling pathways, including neuroprotective PI3K/Akt and Nrf2 pathways, then suppression of pro-apoptotic caspase-3, and suppression of NF-B that reduce the expression of proinflammatory cytokines such as IL-1, and TNF- [50, 86]

So far, drugs with cardioprotective effects have included ACE inhibitors and ARBs, statins, antiplatelet drugs, and beta-blockers