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Impact of heavy metals on breast cancer (Review)

Impaired GSH Synthesis and GSH Deficiency in Aging GSH synthesis is a two-step process where in the first step cysteine first combines with glutamic acid to form the intermediate -glutamylcysteine catalyzed by the enzyme glutamate cysteine ligase (GCL, comprised of catalytic and modifier subunits GCLC and GCLM)

These effects were linked to the activation of signaling pathways such as FAK-paxillin, suggesting a role in regulating cellular movement and structural organization in experimental systems

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Phase 3 SYNCHRONIZE results pending