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Further in vitro and in vivo experiments uncovered metformins ability to suppress oxidative stress by promoting the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2)

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0.5 g (0.35 mmol) BPC157 was dissolved in 8 ml of water containing 114 mg cesium carbonate (0.70 mmol), sterile filtered through a 0.2 filter and lyophilized to give 0.55 g of an off-white solid

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