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Synthesis of ROS-sensitive polymers conjugated with Ru(II)-OH (P4) At room temperature, 4-Dimethylaminopyridine (DMAP, 126 mg) was introduced to a solution of Ru(II)-OH (50 mg) and 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDCl, 200 mg)
At the time, continuous renal replacement therapy (CRRT) was planned, which was started almost 24 hours after presentation
In conclusion, the mechanism underlying PQQ-induced apoptosis may be associated with increasing the levels of ROS, suggesting that PQQ may be a potential drug for chondrosarcoma therapies.
It is a subject of ongoing research for its potential regenerative properties in vitro