7 AngelucciF.SayedA
the minority of persons who have CNSHA are referred to as having rare, sporadic, or severe G6PD deficiency (corresponding to class I)
Hence, these contribute to the reasons for the current inconsistencies in IGF-1 measurements
Fibrosis, or the stage of scarring, can be partially reversed if its detected early
What they found: 4,192 human genes change expression by 2 in response to GHK-Cu (31.2 % of the human genome) Of these 2,296 genes up-regulated , 1,896 down-regulated Pattern of changes: a rejuvenating signature, genes typically associated with ageing are down-regulated, regenerative genes up-regulated DNA repair , strong up-regulation of genes in BER, HR, NER pathways Mitochondrial biogenesis , increase in the number of mitochondria in cells Anti-apoptotic signal , protection against cell death Down-regulation of cancer signals , some oncogenes decreased Why it matters: This is the strongest evidence for the pleiotropic nature of GHK-Cu