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The 250mg dosage is just one option.

2D crystallization The crystallization procedure was performed as described 15 with a different crystallization buffer: 25 mM Tris-HCl at pH 7.4, 20% glycerol, 0.1 mM EDTA, 100 mM KCl, 1 mM GSH, and 50 mM CaCl 2 and crystallization was performed at 30 C

This mechanism is critical because neurons have a limited ability to synthesize endogenous GS ( Oxidative stress in the CNS acts as a persistent inflammatory trigger by activating brain-resident immune cells, particularly microglia and astrocytes

Where those pathways are already functioning well, the effects tend to be small or absent