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The potential effects on fetal development and the unknown presence in breast milk make these peptides inappropriate for use during pregnancy or breastfeeding

No long-term data specifically addresses this question for peptide nasal sprays

BPC-157 peptide (Body Protection Compound-157) stands apart from nearly every other synthetic research peptide for one striking reason: it originates from a protein naturally found in human gastric juice, yet it demonstrates repair activity across at least nine distinct tissue systems in published preclinical studies

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Critically, these effects were achieved without food intake suppression, distinguishing MOTS-c from GLP-1 receptor agonists whose primary mechanism involves appetite reduction