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Importantly, the observed effect cannot be explained (exclusively) as a structure change but rather as a consequence of Zn(II) dissociation due to S-thioallylation

The Shake-Weight Mix: Vigorously shaking the vial to dissolve the powder

J Biol Chem 285:810826

For confirmed deficiency or pernicious anaemia, NICE Clinical Knowledge Summaries recommend hydroxocobalamin 1mg intramuscularly, with frequency determined by the underlying cause and neurological involvement