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This suggests that long-term maintenance on an LD rich in carbohydrates may confound some of the microbiome differences commonly reported between mice on HFDs and those on lean control diets which contain fewer carbohydrates
214 This drop in iron supply could, in turn, increase the potential risk of ID
Beyond its mitogenic and anti-apoptotic effects, IGF-1 exerts immunomodulatory and immunosuppressive actions in various tumor settings, potentially explaining the limited efficacy of immune checkpoint blockade (ICB) in prostate cancer
Various therapeutic modalities are employed, such as alcohol abstinence support, nutritional management (enteral feeding or parenteral feeding), analgesic agents, and antioxidants combined with pancreatic enzyme replacement therapy [92,93,94]
Yimer, E.M., et al
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