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Hold the dose steady for 2 weeks before adjusting

Some clinical trials have investigated glutathiones effects on skin pigmentation, and there is limited evidence that high-dose glutathione supplementation may reduce melanin production over time

Middle cerebral artery (MCA) occlusion, induced with aneurysm clips, was confirmed using 3D-Digital Subtraction Angiography, which was used to quantify the area at risk (AAR) of infarction, as well as tissue perfusion

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At the end of the experiment, brains were collected for cresyl violet staining to confirm cannula placement