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September 19 Product: Johnson & Johnsons Rybrevant Indication: Non-small cell lung cancer Johnson & Johnson racked up its third non-small cell lung cancer (NSCLC) approval for Rybrevant this year as the FDA greenlit the bispecific antibody plus chemotherapy for the second-line treatment of locally advanced or metastatic NSCLC with epidermal growth factor receptor (EGFR) exon 19 deletions or L858R substitution mutations

Room temperature storage and the 21-day rule Sometimes refrigeration is not immediately possible

Dixon and Stockwell, 2014

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These are legitimate reasons to define washouts, but the conversation is different than the receptor needs a rest. Different mechanism, different rationale, different way to think about the timing